Aging Medicine
Aging Medicine Center’s research fields include: physiologic aging and premature aging, the pathogenesis of aging-related diseases, assessment and management of geriatric health and intervention therapies for aging.
We attempting to reveal the pathogenesis of aging-related diseases, and elucidate the tissue-specific mechanism of environmental effects on subhealth and frailty of the elderly, including effects of intestinal microecology, toxin, nutrition and aerobic metabolism imbalance on muscle weakness and other physical disorders. We also investigate mechanism of neuron-specific aging including microelements, lipid metabolism, proteases, degeneration and degradation of macromolecules, organelle stress and replicative aging.
Dynamic monitoring, early warning, assessment and management of elderly health.
Developing intervention therapies for aging and aging-related diseases, including immunotherapy technologies, novel multifunctional molecular imaging probes, antibody-conjugated drugs and small molecular drug targeting technology, biomimetic materials, transplantation of mesenchymal stem cells or mesenchymal stem cell-derived organelles and senolytic gene therapy.
The aim is to discover biology laws for aging, reveal the regulatory mechanism of organ aging and to develop new therapies for aging and aging-related diseases.
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