Research Center

Aging Medicine


Population aging has become a serious problem that the whole world facing and has long-term effect on development of human society. In 2018, for the first time in history, persons aged 65 or above outnumbered children under five years of age globally. The number of persons aged 80 years or over is projected to triple, from 143 million in 2019 to 426 million in 2050. The primary problem brought by population aging is the high incidence of aging-related diseases. Therefore, basic research on common mechanism of organ aging is of great importance.

Core Team

The Centre for Aging Medicine currently consists of one chief scientist, four senior scientists, five researchers, one chief physician and one associate researcher, will provide ongoing high-level clinical translation and cutting-edge multidisciplinary collaboration.

Ying Songmin
Guo Jiangtao
Yang Fan
Kang Lijun
The overall goal of Aging Medicine Centre is to build a world-leading discipline and platform in the field of aging medicine. We are focusing on cutting-edge scientific issues of organ aging and degenerative changes, developing new animal models for aging-related reseach. We are committed to unraveling mechanism of organ aging, achieving clinical application and translation, and building a first-class research team.
Research Fields

Aging Medicine Center’s research fields include: physiologic aging and premature aging, the pathogenesis of aging-related diseases, assessment and management of geriatric health and intervention therapies for aging.

We attempting to reveal the pathogenesis of aging-related diseases, and elucidate the tissue-specific mechanism of environmental effects on subhealth and frailty of the elderly, including effects of intestinal microecology, toxin, nutrition and aerobic metabolism imbalance on muscle weakness and other physical disorders. We also investigate mechanism of neuron-specific aging including microelements, lipid metabolism, proteases, degeneration and degradation of macromolecules, organelle stress and replicative aging.

Dynamic monitoring, early warning, assessment and management of elderly health.

Developing intervention therapies for aging and aging-related diseases, including immunotherapy technologies, novel multifunctional molecular imaging probes, antibody-conjugated drugs and small molecular drug targeting technology, biomimetic materials, transplantation of mesenchymal stem cells or mesenchymal stem cell-derived organelles and senolytic gene therapy.

The aim is to discover biology laws for aging, reveal the regulatory mechanism of organ aging and to develop new therapies for aging and aging-related diseases.