Immunology

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supervisor

Jiawei Shao

Researcher of the "Hundred Talents Program" at Zhejiang University, PhD Supervisor, and High-Level Talent (Leading Scientific and Technological Talent) of Zhejiang Province.

Jiawei Shao
Researcher of the "Hundred Talents Program" at Zhejiang University, PhD Supervisor, and High-Level Talent (Leading Scientific and Technological Talent) of Zhejiang Province.
Research Direction(s)：

Recruitment Fields: Molecular and Cellular Medicine, Immunology

Research Focus: Creation of gene circuits-based solutions for high-precision disease treatment

As the first or corresponding author (including co-authorship), Dr. Shao has published 6 papers in prestigious journals such as Cell, Science Translational Medicine, PNAS, Cell Research, and Nucleic Acids Research. He has filed 9 nationally authorized patents and led research projects including the NSFC General Program, NSFC Young Scientists Program, and served as a key participant in the National Key R&D Program’s Young Scientists Project.


E-mail：
jiaweishao@zju.edu.cn
Personal Homepage：
https://person.zju.edu.cn/jiawei

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Yan Lu

ZJU 100 Young Professor, Ph.D Supervisor

Yan Lu
ZJU 100 Young Professor, Ph.D Supervisor
Research Direction(s)：
Research Direction：1. Molecular and Cellular basis to inflammation and innate immunity； 2. Immunometabolism；3. Protein acylation. Engaged primarily in research concerning innate immunity, metabolism, and the interplay between immunity. Dedicated to exploring the regulatory mechanisms of protein palmitoylation mediated by the palmitoyltransferase family at the cellular, molecular, and whole-animal levels, aiming to elucidate how this modification affects protein function, identify and characterize novel palmitoylated proteins, and propose new signaling pathways. Preliminary research has, for the first time, clarified that the NOD-like receptor family proteins NOD1 and NOD2 can undergo palmitoylation catalyzed by the palmitoyltransferase ZDHHC5, thereby localizing to the plasma membrane and bacterial phagosome membrane to initiate host cell innate immune responses (SCIENCE, first author), which has been recognized with the Zhejiang University Top Ten Academic Progress Award.
E-mail：
yan_l@zju.edu.cn
Personal Homepage：
https://person.zju.edu.cn/0620179

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